Premedication with dexmedetomidine for prevention of hyperdynamic response after electroconvulsive therapy: a cross-over, randomized controlled trial

Phase 4

Completed

• Conditions: Patients with psychiatric disease who undergo electroconvulsive therapy; Dexmedetomidine, Electroconvulsive therapy

• Registration Number: TCTR20170715003
• Lead Sponsor: Department of Anesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-07-15
• Study Completion: 2018-07-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Patients who need electroconvulsive therapy
2. Age 18-70 years old
3. ASA PHYSICAL STATUS 1-3

Exclusion Criteria

1. Pregnancy
2. Hepatic impairment
3. Patients who use beta blocker or narcotic drugs during electroconvulsive therapy
4. Patients who have contraindicated to dexmedetomidine

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure after electroconvulsive therapy 0,2.5,5,7.5,10,15,20,25,30 minute after electroconvulsive therapy non invasive blood pressure cuff,heart rate after electroconvulsive therapy 0,2.5,5,7.5,10,15,20,25,30 minute after electroconvulsive therapy Electrocardiogram

Secondary Outcome Measures

Name	Time	Method
Post electroconvulsive agitation immediately after electroconvulsive therapy Agitation score,asystole duration immediately after electroconvulsive therapy second, Electrocardiogram,seizure duration immediately after electroconvulsive therapy second,seizure threshould immediately after electroconvulsive therapy Joules