Musculoskeletal Symptoms in Post Acute Covid-19 Patients

Completed

• Conditions: Covid19; Musculoskeletal Abnormalities
• Interventions: Other: Survey; Other: Laboratory parameters; Other: chest computed tomography

• Registration Number: NCT04932889
• Lead Sponsor: Eskisehir City Hospital

Brief Summary

The patients whose musculoskeletal symptoms initiated or aggravated with Covid-19, were compared with the patients whose musculoskeletal symptoms did not change with Covid-19. The variables; the demographic and treatment datas, admission symptoms, post acute-Covid-19 symptoms, laboratory, chest computed tomography findings.

Detailed Description

There is a lack of an overview of the factors associated with post acute-Covid-19 musculoskeletal symptoms. The aims are;1-to evaluate the most frequent admission symptoms and the frequency of musculoskeletal symptoms in post acute-Covid-19 patients,2-to determine the related factors with the post acute-Covid-19 musculoskeletal symptoms.

In this retrospective study; the patients whose musculoskeletal symptoms initiated or aggravated with Covid-19, were compared wthe patients whose musculoskeletal symptoms did not change with Covid-19. The variables; the demographic and treatment datas, admission symptoms, post acute-Covid-19 symptoms, laboratory (complete blood count, C-reactive protein, ferritin, D-dimer), chest computed tomography findings.

Study Timeline

• Status Verified: 2021-06
• Study Start: 2021-06-11
• Primary Completion: 2021-06-13
• Study Completion: 2021-06-14
• Study First Submitted: 2021-06-14
• Study First Submitted QC: 2021-06-18
• Last Update Submitted: 2021-06-18
• Study First Posted: 2021-06-21
• Last Update Posted: 2021-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 280

Inclusion Criteria

• Being 18 years or older
• Having Covid-19 treatment (home quarantine / hospital / intensive care unit) according to a positive polymerase chain reaction (PCR) test in a nasopharyngeal + oropharyngeal swab or chest CT.

Exclusion Criteria

• Patients who did not have musculoskeletal symptom records (admission symptoms and musculoskeletal symptoms such as; fatigue, spine / joint /muscle pain/ numbness) in patients files
• Acute Covid-19 patients whose symptoms started less than 1 month

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No change	Laboratory parameters	the patients whose musculoskeletal symptoms did not change with Covid-19 (n=40)
Change	Survey	the patients whose musculoskeletal symptoms initiated or aggravated with Covid-19 (n=240)
Change	Laboratory parameters	the patients whose musculoskeletal symptoms initiated or aggravated with Covid-19 (n=240)
No change	chest computed tomography	the patients whose musculoskeletal symptoms did not change with Covid-19 (n=40)
Change	chest computed tomography	the patients whose musculoskeletal symptoms initiated or aggravated with Covid-19 (n=240)
No change	Survey	the patients whose musculoskeletal symptoms did not change with Covid-19 (n=40)

Primary Outcome Measures

Name	Time	Method
Rate of fatigue	Baseline	given as percentage %
Rate of dyspnea	baseline	given as percentage %
Rate of back pain	Baseline	given as percentage %
Chest computed tomography	Baseline	Presence of covid-19 findings in chest computed tomography (covid findings positive or negative)
Rate of joint pain	Baseline	given as percentage %
Rate of chest pain	Baseline	given as percentage %
Rate of low-back pain	Baseline	given as percentage %
Rate of neck pain	Baseline	given as percentage %
Rate of myalgia	Baseline	given as percentage %

Secondary Outcome Measures

Name	Time	Method
Platelet	Baseline	10\*3 cells/microliter
D-dimer levels	Baseline	miligram/Litre
C-reactive protein	Baseline	miligram/Litre
Hemoglobin	Baseline	gram/desilitre
Duration after the onset of covid-19	Baseline	months
Ferritin	Baseline	nanogram/mililitre
age	Baseline	years
Weight	Baseline	kilograms
gender	Baseline	female or male
Lymhocyte levels	Baseline	10\*3 cells/microliter

Trial Locations

Locations (1)

Eskişehir City Hospital; 🇹🇷 Eskişehir, Turkey