Acute Pain Memory Among Former Burned: Exploration of Functional Magnetic Resonance Imaging (fMRI).
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- BOLD (blood-oxygen-level dependent) signal between control test.
研究概览
简要总结
Pain is complex phenomenon misunderstood in spite of medical progress and neurosciences. That's why the relief of chronic pain is only partial for a lot of infection as arthrosis, chronic back pain, headaches or neuropathic pain. Certain situations bring to relive pain sensation. Investigators were interested to former burned. They wonder about somatic memory and unconscious of acute.
详细描述
It is a comparative and monocentric study. There are two groups. On the one hand, there is the former burned and, on the other hand, healthy volunteers. While they thought to painful memory or not, functional Magnetic Resonance Imaging (fMRI) will be performed. Then, investigators compare two functional Magnetic Resonance Imaging (fMRI).
Main objective of this study is link up between brain activity by functional Magnetic Resonance Imaging (fMRI) and acute pain memory.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For control group:
- •Affiliated or entitled to a social security
- •Have signed consent before their participation in the study
- •Adult women and men french and is right handed
- •Vision and hearing normal or corrected
- •For former burned:
- •Affiliated or entitled to a social security
- •Have signed consent before their participation in the study
- •Adult women and men french and is right handed
- •Vision and hearing normal or corrected
- •Localized burn at the hand or feet onset between 12 and 24 years
- •Not sequelae painful at the inclusion
- •Scope and depth of the burn according to classifications CIM 10
排除标准
- •For control group:
- •Any contraindications to pass an fMRI test
- •Neuropathic pains and psychiatric disorders
- •Medical history of head injuries
- •Burn presence
- •For former burned:
- •Any contraindications to pass an fMRI test
- •Neuropathic pains and psychiatric disorders
- •Medical history of head injuries
结局指标
主要结局
BOLD (blood-oxygen-level dependent) signal between control test.
时间窗: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between emotional memories not painful
时间窗: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between neutral memories
时间窗: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between painful memories
时间窗: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
次要结局
- BOLD (blood-oxygen-level dependent) signal between patients for every conditions(Months 3)
- BOLD (blood-oxygen-level dependent) signal between control group for every conditions(Months 3)