Acute Pain Memory Among Former Burned: Exploration of Functional Magnetic Resonance Imaging (fMRI).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Magnetic Resonance Imaging
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- BOLD (blood-oxygen-level dependent) signal between control test.
- Status
- Terminated
- Last Updated
- 5 years ago
Overview
Brief Summary
Pain is complex phenomenon misunderstood in spite of medical progress and neurosciences. That's why the relief of chronic pain is only partial for a lot of infection as arthrosis, chronic back pain, headaches or neuropathic pain. Certain situations bring to relive pain sensation. Investigators were interested to former burned. They wonder about somatic memory and unconscious of acute.
Detailed Description
It is a comparative and monocentric study. There are two groups. On the one hand, there is the former burned and, on the other hand, healthy volunteers. While they thought to painful memory or not, functional Magnetic Resonance Imaging (fMRI) will be performed. Then, investigators compare two functional Magnetic Resonance Imaging (fMRI). Main objective of this study is link up between brain activity by functional Magnetic Resonance Imaging (fMRI) and acute pain memory.
Investigators
Eligibility Criteria
Inclusion Criteria
- •For control group:
- •Affiliated or entitled to a social security
- •Have signed consent before their participation in the study
- •Adult women and men french and is right handed
- •Vision and hearing normal or corrected
- •For former burned:
- •Affiliated or entitled to a social security
- •Have signed consent before their participation in the study
- •Adult women and men french and is right handed
- •Vision and hearing normal or corrected
Exclusion Criteria
- •For control group:
- •Any contraindications to pass an fMRI test
- •Neuropathic pains and psychiatric disorders
- •Medical history of head injuries
- •Burn presence
- •For former burned:
- •Any contraindications to pass an fMRI test
- •Neuropathic pains and psychiatric disorders
- •Medical history of head injuries
Outcomes
Primary Outcomes
BOLD (blood-oxygen-level dependent) signal between control test.
Time Frame: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between emotional memories not painful
Time Frame: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between neutral memories
Time Frame: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
BOLD (blood-oxygen-level dependent) signal between painful memories
Time Frame: Months 3
Correlation between BOLD measured by functional Magnetic Resonance Imaging (fMRI) and every conditions: painful memories, emotional memories not painful, neutral memories and control test.
Secondary Outcomes
- BOLD (blood-oxygen-level dependent) signal between patients for every conditions(Months 3)
- BOLD (blood-oxygen-level dependent) signal between control group for every conditions(Months 3)