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临床试验/NCT04407065
NCT04407065
Unknown
2 期

Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles. A Randomized Controlled Trial

Riyadh Fertility and Reproductive Health center1 个研究点 分布在 1 个国家目标入组 56 人2020年5月30日

概览

阶段
2 期
干预措施
Double trigger
疾病 / 适应症
Infertility, Female
发起方
Riyadh Fertility and Reproductive Health center
入组人数
56
试验地点
1
主要终点
Number of oocytes retrieved
最后更新
5年前

概览

简要总结

The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in patients with history of poor oocytes yield, despite normal response to COH, due to low (<50%) number of oocytes retrieved per number of follicles > 14 mm in diameter on day of hCG administration

注册库
clinicaltrials.gov
开始日期
2020年5月30日
结束日期
2021年2月2日
最后更新
5年前
研究类型
Interventional
研究设计
Parallel
性别
Female

研究者

发起方
Riyadh Fertility and Reproductive Health center
责任方
Sponsor

入排标准

入选标准

  • Patients with history of poor oocytes yield in previous IVF attempt, despite normal response to COH, due to low (\<50%) number of oocytes retrieved per number of follicles \> 14 mm in diameter on day of hCG administration
  • Patients with 6 to 15 mature follicles on the day oocyte trigger in the current IVF-ET attempt

排除标准

  • Endometriosis

研究组 & 干预措施

Double trigger

GnRH-agonist and HCG are used to trigger ovulation

干预措施: Double trigger

HCG

HCG is used to trigger ovulation

干预措施: HCG trigger

结局指标

主要结局

Number of oocytes retrieved

时间窗: First day after oocyte retrieval

次要结局

  • clinical pregnancy rate(First 5 weeks after oocyte retrieval)

研究点 (1)

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