High vs Normal Protein Diets, Resistance Exercise, Lean Mass and Strength Gains

Not Applicable

• Conditions: Sarcopenia
• Interventions: Other: High protein; Other: Normal protein; Other: Training

• Registration Number: NCT03024125
• Lead Sponsor: Federal University of Uberlandia

Brief Summary

This study evaluates the effect of different types of diets (high and normal protein) on lean and fat mass, and strength in postmenopausal women practitioners of resistance exercise. Two groups will be created: high protein (1.2 protein g/body mass/day) and normal protein (0.8 protein g/body mass/day). The same training will be performed for both groups.

Detailed Description

Both groups will undergo the same training protocol, differing only on the protein content of the diet. The dietary assessment will be made through the 24-hour food recall, being conducted at the beginning, middle and end of the intervention. Resistance exercises for upper and lower limbs will be performed, at 70% of one repetition maximum. SPPB, tug, 6-minutes and 400 meters will be performed.

Study Timeline

• Study Start: 2016-05
• Primary Completion: 2016-08
• Study First Submitted: 2016-10-31
• Status Verified: 2017-01
• Study First Submitted QC: 2017-01-17
• Last Update Submitted: 2017-01-17
• Study First Posted: 2017-01-18
• Last Update Posted: 2017-01-18
• Study Completion: 2017-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased);
• Healthy;
• Who agree to participate and sign the consent term.

Exclusion Criteria

• The one who does not provide the necessary information for the development of the study;
• Present orthopedic limitations;
• Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High protein diet (HP)	High protein	Diet with 1.2 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups
High protein diet (HP)	Training	Diet with 1.2 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups
Normal protein diet (NP)	Normal protein	Diet with 0.8 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups
Normal protein diet (NP)	Training	Diet with 0.8 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups

Primary Outcome Measures

Name	Time	Method
Changes in the lean mass of postmenopausal women practicing strength exercise	Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention)

Secondary Outcome Measures

Name	Time	Method
Changes on strength of postmenopausal women practicing strength exercise	Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention)
Changes in the fat mass of postmenopausal women practicing strength exercise	Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention)