Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)

Completed

• Conditions: Normal Pressure Hydrocephalus
• Interventions: Device: Computerized neuropsychological test; Other: Conventional neuropsychological test

• Registration Number: NCT01265251
• Lead Sponsor: Umeå University

Brief Summary

A computerised neuropsychological test battery to be used as a standardised tool assessing the cognitive domains affected by idiopathic normal pressure hydrocephalus INPH was developed. The aim of this study is to investigate the reliability, validity and feasibility of the battery.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Primary Completion: 2010-04
• Study Completion: 2010-04
• Status Verified: 2010-12
• Study First Submitted: 2010-12-21
• Study First Submitted QC: 2010-12-22
• Last Update Submitted: 2010-12-22
• Study First Posted: 2010-12-23
• Last Update Posted: 2010-12-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

• Probable INPH under investigation
• Healthy elderly
• Various diseases

Exclusion Criteria

• (Healthy elderly) medications affecting nervous system
• (Healthy elderly)heart disease
• (Healthy elderly)diabetes
• (Healthy elderly)disease of the nervous system
• (Healthy elderly)MMSE < 28
• (Healthy elderly)vascular risk factors (Two of: 1 hypertension, 2 smoking or 3 hyperlipidemia)
• (Healthy elderly)serious disease that may shorten life expectancy
• (Various diseases) Affected motor functions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Validity	Computerized neuropsychological test	Twenty six patients with various diseases and various ages
Validity	Conventional neuropsychological test	Twenty six patients with various diseases and various ages
Feasibility	Computerized neuropsychological test	Twenty seven patients under the preoperative investigation for INPH
Test-retest	Computerized neuropsychological test	Forty-four healthy elderly 60-82 years old

Primary Outcome Measures

Name	Time	Method
Validity	Within 24 h	Computerized test battery and equivalent standard neuropsychological test battery is given to the same subject. Correlation between paper and pen and equivalent computerized test is calculated as a validity measure.
Reliability	More than 7 days, within 2 months	The computerized test battery is given to the same subject twice. Correlation between the two tests is calculated as a test-retest reliability measure.
Feasibility	Within 24 h	Patients under the investigation for INPH are given the computerized test battery. Number of patients who manage to complete the test is the feasibility measure.

Trial Locations

Locations (1)

Department of Clinical Neuroscience; 🇸🇪 Umeå, Västerbotten, Sweden