Transversus Abdominis and Transversalis Fascia Plane Block Combination for Cesarean Section

Not Applicable

Completed

• Conditions: Ceserean Section and Postoperative Pain

• Registration Number: NCT06944912
• Lead Sponsor: Ataturk University

Brief Summary

Cesarean delivery rates are rising globally, and effective postoperative analgesia is crucial for maternal recovery and newborn care. While intrathecal morphine offers strong analgesia, it may cause side effects such as nausea, pruritus, or respiratory depression. The transversus abdominis plane (TAP) block provides somatic pain relief but is often insufficient alone. The transversalis fascia plane block (TFPB) has been shown to enhance lower abdominal analgesia. This study aims to evaluate whether combining TAP and TFP blocks can provide analgesic efficacy comparable to intrathecal morphine in cesarean section patients who are unable to receive opioids or are at high risk of side effects.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Primary Completion: 2025-01-01
• Study Completion: 2025-03-01
• Status Verified: 2025-04
• Study First Submitted: 2025-04-18
• Study First Submitted QC: 2025-04-18
• Last Update Submitted: 2025-04-24
• Study First Posted: 2025-04-25
• Last Update Posted: 2025-04-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• 18-45 years old
• American Society of Anesthesiologists physical score I or II
• caesarean section with a Pfannenstiel incision

Exclusion Criteria

• additional surgical intervention, or received general anaesthesia,
• hypersensitivity to the agents to be used
• BMI greater than 35 kg m-2
• coagulopathy,
• local infection,
• opioid addiction,
• pregnancy-related hypertension
• diabetes mellitus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The Obstetric Quality of Recovery-10 (ObsQoR-10) Score	Postoperative 24 hours	The questionnaire's subscales are physical comfort (n=3 items), emotional state (n=2 items), pain (n=1 item), physical independence (n=2 items), and the ability to take care of the newborn (n=2 items). Each item is scored on a scale of 0-10, except for the first four items, which are graduated from 10 to 0. The total score is the sum of all item scores (i.e. a score ranging from 0 to 100, where 0 is the worst recovery score, and 100 indicates the best).

Secondary Outcome Measures

Name	Time	Method
Opioid consumption	Postoperative 24. hours	Patient controlled analgesia based opioid requirement

Trial Locations

Locations (1)

Atatürk University Hospital; 🇹🇷 Erzurum, Yakutiye, Turkey