Multimodal Intrathecal Analgesia for Cesarean Section
试验速览
- 阶段
- 2 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1st analgesic requirement
研究概览
简要总结
Cesarean section is one of the painful operations that require adequate postoperative analgesia. Patients are divided into two groups: Multimodal (DMM) group ( 30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam.
Morphine (M) group (30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 200 µg morphine
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Morphine
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 200 µg of morphine intrathecally.
干预措施: Bupivacaine (Drug)
Morphine
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 200 µg of morphine intrathecally.
干预措施: Morphine Sulfate (Drug)
Multimodal
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam intrathecally
干预措施: Bupivacaine (Drug)
Multimodal
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam intrathecally
干预措施: dexamethasone, morphine, midazolam (Drug)
结局指标
主要结局
1st analgesic requirement
时间窗: 24 hours
The first time of supplemental analgesic need postoperatively
次要结局
- Analgesic consumption(24 hours)
- Post operative pain(24 hours)
- Side effects(24 hours)
研究者
Fouad Soliman
Lecturer of Anesthesia and ICU
Sohag University