Multimodal Intrathecal Analgesia for Cesarean Section
Overview
- Phase
- Phase 2
- Intervention
- Bupivacaine
- Conditions
- Post Operative Pain
- Sponsor
- Sohag University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- 1st analgesic requirement
- Last Updated
- 4 years ago
Overview
Brief Summary
Cesarean section is one of the painful operations that require adequate postoperative analgesia. Patients are divided into two groups: Multimodal (DMM) group ( 30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam.
Morphine (M) group (30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 200 µg morphine
Investigators
Fouad Soliman
Lecturer of Anesthesia and ICU
Sohag University
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
Morphine
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 200 µg of morphine intrathecally.
Intervention: Bupivacaine
Morphine
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 200 µg of morphine intrathecally.
Intervention: Morphine Sulfate
Multimodal
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam intrathecally
Intervention: Bupivacaine
Multimodal
Patients will receive 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam intrathecally
Intervention: dexamethasone, morphine, midazolam
Outcomes
Primary Outcomes
1st analgesic requirement
Time Frame: 24 hours
The first time of supplemental analgesic need postoperatively
Secondary Outcomes
- Analgesic consumption(24 hours)
- Post operative pain(24 hours)
- Side effects(24 hours)