Study on the central-peripheral regulation mechanism of ocular acupuncture kinesitherapy for post-stroke dyskinesia

Phase 1

• Conditions: post-stroke dyskinesia

• Registration Number: ITMCTR2200006052
• Lead Sponsor: Hospital of Chengdu University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patients meet with following 5 criteria can be included in this study:
1.diagnosed as stroke for the first time with lateral dyskinesia;
2.right-handed between 30-80 years old;
3.no metallic objects in the body, no fMRI or TMS contraindications;
4.who have not received disease-related acupuncture and exercise therapy in the last 1 month;
5.Who knows and agree with relevant research content and signs the informed consent form.

Exclusion Criteria

Patients meet with 1 of the following 8 criteria will be excluded in this study:
1.Dyskinesia caused by other diseases and causes, such as Parkinson's disease, Parkinson's syndrome, progressive supranuclear palsy, hepatolenticular degeneration, essential tremor, multiple system atrophy, chorea, throwing syndrome, myoclonus, dystonia, tourette syndrome, and so on;
2.With serious diseases, such as uncontrollable hypertension, arrhythmia, serious coronary heart disease, diabetes complications are not well controlled, or have epilepsy, serious organ failure and second attack of stroke, and so on;
3.With unstable vital signs;
4.Who is susceptible to co-infection, bleeding, tumor, pregnant women, postoperative dysfunction patients;
5.Who receives other traditional Chinese medicine rehabilitation intervention except acupuncture and pestle during treatment;
6.with language or cognitive impairment, therefore can not understand the instructions to communicate or cooperate;
7.with previous mental illness history or long-term use of sedatives;
8.with forbidden exercising diseases;

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
fMRI brain function;TMS-MEP motor evoked potential;

Secondary Outcome Measures

Name	Time	Method
Biochemical criterion;Simplify Fugl-Meyer scoring;MMT freehand muscle strength grading;General indicators;