deep brain stimulation in patients with refractory epilepsy

Not Applicable

• Conditions: G40.2; Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

• Registration Number: DRKS00003148
• Lead Sponsor: niversitätsklinik für Stereotaktische Neurochirurgie des Universitätsklinikums Magdeburg AöR

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-07-04
• Study Completion: 2015-01-01
• Results First Posted: 2015-05-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

pharmaco-refractary partial epilepsy with at least three disabling seizures in four week during the past three months

Exclusion Criteria

psychiatric and/or internal relevant comorbidity, psychogenic non-epileptic seizures, progressive degenerative neurological disease, custodial guardianship

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fraction of patients with at least 50% reduction of seizure-frequency after three months of deep brain stimulation in comparison with the untreated controls.

Secondary Outcome Measures

Name	Time	Method
Change of seizure severity assessed with the Liverpool Seizure Severity Scale (assessment: at enrolment, after 3 month, 1 month post-implantation, 4 month post-implantation, 5 month post-implantation, 8 month post-omplantation, 9 month post-implantation, 12 month post-implantation)