EUCTR2020-004913-11-NL进行中（未招募）1 期
genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease’ - GENPAD
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- Radboudumc
- 入组人数
- 2,244
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- age > 16 years
- •- obtained written informed consent
- •- indication for monotherapy clopidogrel 75mg once daily
- •- ankle-brachial index < 0.9 and/or toe brachial index < 0.5
- •- current or previous symptoms due to insufficient vascularization of one or two lower extremities, including intermittent claudication, pain at rest and/or gangrene (Rutherford category 1-6)
- •- consulting a vascular surgeon for diagnosis, treatment and/or follow-up of PAD symptoms
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 744
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 1500
排除标准
- •- known CYP2C19*2 and *3 status
- •- treated with coumarins, Non-vitamin K Oral Anti-Coagulants, unfractionated heparin, low molecular weight heparins or double antiplatelet therapy for other indications
- •- contraindication for clopidogrel, acetylsalicylic acid and/or rivaroxaban
- •- life expectancy of less than 1 year
- •- pregnant or breastfeeding women
- •- unable to give informed consent
研究者
相似试验
招募中
4 期
Genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease.Peripheral arterial diseaseNL-OMON50838Academisch Medisch Centrum2,276
招募中
不适用
Genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease.Peripheral arterial diseaseNL-OMON26517Radboudumc2,276
招募中
4 期
Genotype-guided Strategy for Antithrombotic Treatment in Peripheral Arterial Disease.Peripheral Arterial DiseaseNCT04619927Radboud University Medical Center2,276
尚未招募
不适用
Antithrombotic strategies for treatment of patients with ventricular thrombus after myocardial infarction and association of outcomes: a retrospective analysisI51.3I21Intracardiac thrombosis, not elsewhere classifiedAcute myocardial infarctionDRKS00032548niversitätsklinikum Freiburg200
尚未招募
Unknown
Optimal antithrombotic strategy for treatment of atherosclerotic cardiovascular disease – comparison of clopidogrel-based antiplatelet agent treatment versus aspirin plus low dose rivaroxaban therapy (OACART study)KCT0008458Seoul National University Bundang Hospital2,758