NL-OMON50838招募中4 期
Genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease. - GENPAD
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 2,276
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- age > 16 years
- •- obtained written informed consent
- •- indication for monotherapy clopidogrel 75mg once daily
- •- ankle-brachial index < 0.9 and/or toe brachial index < 0.5
- •- current or previous symptoms due to insufficient vascularization of one or
- •two lower extremities, including intermittent claudication, pain at rest and/or
- •gangrene (Rutherford category 1-6)
- •- consulting a vascular surgeon for diagnosis, treatment and/or follow-up of
- •PAD symptoms
排除标准
- •- known CYP2C19*2 and *3 status
- •- treated with coumarins, Non-vitamin K Oral Anti-Coagulants, unfractionated
- •heparin, low molecular weight heparins or double antiplatelet therapy for other
- •indications
- •- contraindication for clopidogrel, acetylsalicylic acid and/or rivaroxaban
- •- life expectancy of less than 1 year
- •- pregnant or breastfeeding women
- •- unable to give informed consent
研究者
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