The effect of acute ketone monoester supplementation on glucose oxidation during exercise performed with high rates of carbohydrate ingestion in trained cyclists
- Conditions
- This study will evaluate the effect of exogenous ketone mono-ester supplementation on endogenous and exogenous carbohydrate metabolism during exerciseenergy metabolismfuel selection during exercise
- Registration Number
- NL-OMON53385
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 27
- 18-50 years of age
- Trained cyclist/triathlete ((VO2peak > 55 ml/kg/min for males and >48
ml/mg/min for females)
- Healthy as per medical history and investigator*s/physician*s judgement
- Having given written informed consent
- Use of medication that could impact study outcomes and/or interfere with the
expected mechanism of action of ketone supplements (e.g. Chronic use of gastric
acid suppressing medication, statins, corticosteriods)
- Smoking
- Diagnosed acute or chronic medical conditions that, in the opinion of the
investigator, could impact study outcomes (e.g. Diabetes mellitus)
- Diagnosed musculoskeletal disorders
- Adhering to a carbohydrate restrictive diet
- Participation in another study at the same time
- Blood donation in the 2 months before the first experimental trial
- Plasma donation in the 2 weeks before the first experimental trial
- Males: VO2peak <55 ml/min/kg body mass
- Females: VO2peak <48 ml/min/kg body mass
- Females: pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method