Delayed Dinner, Exercise and Glucose Metabolism

Not Applicable

Recruiting

• Conditions: Delayed Dinner; Normal Dinner; Exercise Plus Delayed Dinner

• Registration Number: NCT05795205
• Lead Sponsor: National Taiwan Normal University

Brief Summary

This study aims to investigate whether exercise can alleviate the impact of delayed dinner on metabolic health next morning in sedentary healthy adults

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-15
• Study First Submitted: 2023-03-21
• Study First Submitted QC: 2023-03-21
• Status Verified: 2023-04
• Study First Posted: 2023-04-03
• Last Update Submitted: 2023-04-04
• Last Update Posted: 2023-04-07
• Primary Completion: 2023-08-15
• Study Completion: 2023-08-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• Physical inactive males
• Weight stable for more than 3 months (no change in weight +/- 3%)
• Non-smoker
• Able to walk comfortably on a treadmill
• Dinner consumers with normal sleep pattern (cycles)

Exclusion Criteria

• Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
• Taking medications that may influence lipid or carbohydrate metabolism or immune system function
• Unable to take part in exercise for any reason (e.g., injury or disability) or a positive response to any questions on the Physical Activity Readiness questionnaire (PAR-Q)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Metabolic health (Oral glucose tolerance test, OGTT)	120 minutes	Fasting and postprandial blood insulin responses on next morning between trials

Secondary Outcome Measures

Name	Time	Method
HRV	Baseline	Heart rate variability on next morning between trial
Inflammation	Baseline	Fasting inflammatory biomarkers (IL-6, TNF-a, CRP) on next morning between trials
Blood pressure	120 minutes	Changes in blood pressure (systolic and diastolic blood pressure) on next morning between trials
Visual analogue scale (VSA)	120 minutes	Changes in VAS from 0-100 mm (e.g., appetite \& mood, etc.) on next morning between trials
Substate oxidation	120 minutes	Lipid and carbohydrate oxidation during OGTT between trials
Appetite (lunch intake)	30 minutes	Ab libitum energy intake on next morning by the end of trial
Gut hormones	120 minutes	Changes in blood gut hormones responses on next morning (e.g., GLP-1, PYY and GIP) between trials

Trial Locations

Locations (1)

National Taiwan Normal University; 🇨🇳 Taipei, Taiwan