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eurocognitive functioning and functional connectivity in meningioma patients: a magnetoencephalography study

Conditions
brain tumor
cancer
10029211
Registration Number
NL-OMON30843
Lead Sponsor
Vrije Universiteit Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

(1) Adult (> 18 years), (2) histologically proven meningioma WHO grade I, (3) no clinical or radiological signs of tumor progression for at least one year prior to inclusion date, (4) end of treatment at least one year prior to inclusion, and (5) written informed consent.

Exclusion Criteria

(1) Use of centrally acting drugs, including corticosteroids, other than antiepileptic drugs, (2) a medical condition that interferes with normal cognitive functioning, (3) cerebrovascular pathology, (4) congenital CNS malformations, (5) multiple sclerosis, (6) Parkinson*s disease, (7) psychiatric disease or symptoms, (8) optic nerve meningiomas, (9) insufficient mastery of the Dutch language, and (10) inability to communicate adequately.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Main study parameters are cognitive functioning (measured by an extensive<br /><br>neuropsychological test battery) and MEG-measures of functional connectivity<br /><br>(synchronization likelihood). </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>n.v.t.</p><br>
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