Comparison of the effects of propofol monotherapy and propofol ketamine combination therapy on the development of post-sedation atelectasis in pediatric sedation for MRI scans: prospective randomized controlled study
- Conditions
- Not Applicable
- Registration Number
- KCT0007699
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 108
? Pediatric patients undergoing MRI scan under sedation anesthesia
? 3 years to 12 years old
? American Society of Anesthesiologists physical status classification1, 2
Premature infants,
History of previous chest surgery,
Patients with confirmed upper or lower respiratory tract infections,
Patients with airway malformations,
Patients with severe lung disease
Patients with Body mass index >= 30
Preoperative chest X-ray abnormal findings (eg atelectasis, pneumonia, pneumothorax, pleural effusion, etc.)
Patients with increased intracranial pressure or intraocular pressure
Patients with uncontrolled hypertension
History of convulsions or seizures
Patients with hypersensitivity to this drug
Patients with hypersensitivity to soybeans or peanuts
Patients with cerebrovascular disorders and severe heart failure
Patients with insufficiently treated hyperthyroidism
Patients with severe cardiac decompensation
Pregnant or possibly pregnant women, and lactating women.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of atelectasis after sedation
- Secondary Outcome Measures
Name Time Method airway intervention;Vital sign: Heart rate, Blood pressure, SpO2;complication of sedation: aspiration, hypoxia, poor quality of MRI scan, hypertension, hypotension, bradycardia, tachycardia;any complications after sedation ;postoperative nausea and vomiting;pulmonary complications;parasternal muscle thickness