MedPath

Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia

Not Applicable
Completed
Conditions
Postoperative Pain After Knee Arthroscopy
Interventions
Registration Number
NCT03530280
Lead Sponsor
Ankara Diskapi Training and Research Hospital
Brief Summary

arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.

Detailed Description

Patients who American Society of Anesthesiologists (ASA) classification I to II scheduled to undergo arthroscopically assisted ACL reconstructions under spinal anesthesia are included in this study. The first group is administered 150 mg oral pregabalin 1 hour before surgery and the postoperative sham block was performed with an ultrasound probe. The second group is the control group; patients in this group are administered a placebo capsule 1 hour before surgery and sham block was performed with an ultrasound probe.The third group is administered a placebo capsule 1 hour before surgery and postoperative adductor canal block is performed. All patients will be received postoperative a tramadol i.v. patient control analgesia device. At the end of 24 hours, the total amount of tramadol consumed by the patient will be recorded from the patient control analgesia. NRS score, white fast track, satisfaction will be questioned.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
51
Inclusion Criteria
  • Patients between the ages of 18 and 70 years
  • American Society of Anesthesiologists I or II
  • Scheduled to undergo knee arthroscopy
Exclusion Criteria
  • allergic to any medicines
  • History of drug or alcohol abuse,
  • Opioids or sedative medications
  • History of psychiatric conditions
  • Pregnant or lactating women

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
pregabalin (lyrica)pregabalin (lyrica)pregabalin (lyrica) 150 mg preoperative 1 hour before and the postoperative sham block will perform.
placebo groupPlacebo oral tableta placebo capsule 1 hour before surgery and the postoperative sham block will perform.
adductor channel block groupadductor canal block including bupivacaineA preoperative placebo capsule will be given.This group will receive postoperative adductor channel block including 10 mL of 0.25% bupivacaine with 5 μg/mL epinephrine
Primary Outcome Measures
NameTimeMethod
tramadol consumption24 hours

24 hours tramadol consumption will be recorded as milligrams

11-point numerical rating scale (NRS)24 hours

11-point numerical rating scale for pain (0='no pain' and 10='worst pain possible pain') were explained.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Diskapi Teaching and Research Hospital

🇹🇷

Ankara, Altindag, Turkey

© Copyright 2025. All Rights Reserved by MedPath