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Effects of Concurrent HIIT and WB-EMS Exercise on the Cardiometabolic Risk Profile in Obese Individuals

Not Applicable
Conditions
Metabolic Syndrome
Overweight and Obesity
Interventions
Other: HIIT + CST
Other: HIIT + WB-EMS
Other: WB-EMS + HIIT
Other: CST + HIIT
Registration Number
NCT03710447
Lead Sponsor
University of Erlangen-Nürnberg Medical School
Brief Summary

The main purpose of this study is to compare the impact of concurrent high-intensity interval training (HIIT) and whole-body electromyostimulation exercise (WB-EMS) or low-volume conventional strength training (CST) on the cardiometabolic risk profile, overall physical fitness (cardiorespiratory fitness and muscular strength), body composition, inflammatory markers and subjective health outcomes after a 12-week intervention trial in overweight individuals at increased cardiometabolic risk. Furthermore, this study aims to investigate the influence of intra-session exercise order on all outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Body Mass Index >25
  • presence of at least 2 cardiometabolic risk factors
Exclusion Criteria
  • Healthy persons or patients under age
  • Overweight persons without any additional cardiometabolic risk factors
  • Pregnancy, Lactation
  • Psychological disorders, epilepsy, sever neurological disorders
  • Participation in other exercise- or nutrition studies within the last 6 months
  • acute cardiovascular disease
  • malignant disease
  • Electronic implants (defibrillator, pacemaker)
  • Persons in mental hospitals by order of authorities or jurisdiction

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
HIIT + CSTHIIT + CSTHigh-intensity interval training (HIIT) combined with conventional low-volume strength training (CST) Sequence of application: HIIT - CST
HIIT + WB-EMSHIIT + WB-EMSHigh-intensity interval training (HIIT) combined with whole-body electromyostimulation (WB-EMS) Sequence of application: HIIT - WB-EMS
WB-EMS + HIITWB-EMS + HIITWhole-body electromyostimulation (WB-EMS) combined with High-intensity interval training (HIIT) Sequence of application: WB-EMS - HIIT
CST + HIITCST + HIITConventional low-volume strength training (CST) combined with high-intensity interval training (HIIT) Sequence of application: CST - HIIT
Primary Outcome Measures
NameTimeMethod
Change in Metabolic Syndrome Z-Score (MetS-Z-Score).12 weeks

MetS-Z-Score will be calculated from each individual's measures of waist circumference, mean arterial blood pressure, triglycerides, and HDL-cholesterol, based on equations specific to sex.

Change in overall Physical Fitness Score (PFS)12 weeks

PFS is calculated from VO2max and 1 Repmax values of 5 major muscle Groups.

Secondary Outcome Measures
NameTimeMethod
Change in HOMA-IR12 week

Insulin resistance will be estimated using homeostasis model assessment index (HOMA)

Change Inflammation status12 weeks

Inflammation will be assessed by measuring levels of inflammatory blood markers (CRP, inflammatory cytokines)

Change in Health-related quality of life12 weeks

Health-related quality of life will be assessed by using the standardized and validated EQ-5D-5L Questionnaire

Change in Perceived stress12 weeks

Perceived stress will be assessed by using the standardized and validated Perceived Stress Questionnaire (PSQ)

Change in Pain scores12 weeks

Pain scores will be assessed by using the standardized and validated Chronic Pain Grade Questionnaire (CPGQ)

Change in Body Composition12 weeks

Muscle mass, fat mass and body water will be measured by Bioelectrical Impedance Analysis (BIA)

Change Subjective work ability12 weeks

Subjective work ability will be assessed by using the standardized and validated Work Ability Index Questionnaire (WAI)

Trial Locations

Locations (1)

Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg

🇩🇪

Erlangen, Germany

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