Functional Brain Imaging - Acupuncture and Osteoarthritis
- Conditions
- Osteoarthritis
- Interventions
- Procedure: acupuncture
- Registration Number
- NCT00070824
- Brief Summary
The goal of this study is to use single photon emission computed tomography (SPECT) and functional magnetic resonance imaging (f-MRI) of the brain to study the response of both normal participants and participants with Osteoarthritis (OA) of the knee to acupuncture.
- Detailed Description
Recent experimental studies in both animal and humans have begun to demonstrate some measurable physiologic effects that are associated with acupuncture, suggesting the possibility of a neurophysiologic explanation. In addition, brain research continues to uncover a complex set of endogenous neurologic control systems, such that it has become clear that the brain plays a major role in the modulation of pain perception and control. If acupuncture can be demonstrated to have a consistent effect on specific areas of the brain, it will become possible to explore the potential efficacy of acupuncture based on measurable neurophysiologic responses.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description B acupuncture Patients with osteoarthritis pain at rest A acupuncture Normal Subjects without pain
- Primary Outcome Measures
Name Time Method SPECT Cerebral Bloodflow 24 hours
- Secondary Outcome Measures
Name Time Method 0-10 Numeric Rating Scale for Pain Intensity 1 hour
Trial Locations
- Locations (1)
Hospital of the University of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States