Effects of High-intensity Interval Training on Cardiorespiratory Performance and Substrate Oxidation in Insulin-resistant and Insulin-sensitive Obese Adolescents: A Before-and-after Clinical Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
- Enrollment
- 25
- Locations
- 3
- Primary Endpoint
- rate of Intensity at first ventilatory anaerobic threshold (VAT1)
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Evaluate the effects of HIT on the cardiorespiratory performance and substrate oxidation of insulin-resistant and insulin-sensitive obese adolescents.
Detailed Description
Objective: To evaluate the effect of high-intensity interval training (HIT) on the cardiorespiratory performance and substrate oxidation pattern in insulin-resistant and insulin-sensitive obese adolescents.
Investigators
JULIANA MONIQUE LINO
Principal investigator Juliana Monique Lino Aparecido
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Eligibility Criteria
Inclusion Criteria
- •aged 12-16 years
- •with a body mass index z-score (zBMI) ≥ + 2SD
- •puberty stage \> 3
- •the boys and girls had to present a minimum physical fitness, according to the International Physical Activity Questionnaire (IPAQ), according to the activity performed during the last week and confirmed this using the peak cardiopulmonary test (VO2).
Exclusion Criteria
- •individuals undergoing drug treatment for weight control;
- •indiviudals who had cardiac, orthopedic, respiratory or renal problems, diabetes, uncontrolled hypertension, genetic syndrome or hormonal abnormalities.
Outcomes
Primary Outcomes
rate of Intensity at first ventilatory anaerobic threshold (VAT1)
Time Frame: 4 weeks
The cardiopulmonary test protocol included running on a treadmill (Model ATL, Inbrasport Ltda; Brazil) at a speed of 4 km/h with 1 km/h increments every minute until the participant showed exhaustion. We evaluated ventilatory parameters on a gas analyzer (model VO2000; Inbrasport Ltda; Brazil).We determined VAT1 (ml/kg/min) using the V-slope method of Beaver et al.
rate of Peak Heart rate
Time Frame: 4 weeks
The cardiopulmonary test protocol included treadmill running (Model ATL, Inbrasport Ltda; Brazil). speed of 4 km / h with increments of 1 km / h every minute until the participant shows exhaustion.
rate of carbohydrate oxidation
Time Frame: 4 weeks
The substrate oxidation pattern protocol included treadmill running (Model ATL, Inbrasport Ltda; Brazil),during continuous exercise of submaximal intensity (45 minutes of treadmill running at the intensity of the first ventilatory anaerobic threshold).
rate of Peak oxygen consumption (VOpeak)
Time Frame: 4 weeks
The cardiopulmonary test protocol for determination the VOpeak (ml/kg/min) included running on a treadmill (Model ATL, Inbrasport Ltda; Brazil) at a speed of 4 km/h with 1 km/h increments every minute until the participant showed exhaustion. We evaluated ventilatory parameters on a gas analyzer (model VO2000; Inbrasport Ltda; Brazil).
rate of lipid oxidation
Time Frame: 4 weeks
The substrate oxidation pattern protocol included treadmill running (Model ATL, Inbrasport Ltda; Brazil),during continuous exercise of submaximal intensity (45 minutes of treadmill running at the intensity of the first ventilatory anaerobic threshold).