Regional Activation of Leukocytes in Coronary artery disease And Diabetes mellitus (REAL-CAD)

Recruiting

• Conditions: atherosclerosis; coronary artery disease; 10011082; 10018424; 10003216

• Registration Number: NL-OMON30068
• Lead Sponsor: Sint Franciscus Gasthuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

Subjects scheduled to undergo a coronary catheterization
Aged >18 and <75 years
BMI < 35 kg/m2

Exclusion Criteria

Emotionally and intellectually not capable to decide about participation in the study and the consequences of participation. Subjects who are not able to understand the patient information
Unstable angina pectoris
CABG or PTCA during the last 6 months
Alcohol use > 2 units/day
Aberrations in kidney, liver and thyroid function
Use of any experimental medication within 6 months of the catheterization
The use of immunosuppressive drugs

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In this study the inflammation (leukocyte activation markers and complement<br /><br>components) in different vascular beds end the relation with triglycerides and<br /><br>glucose will be investigated in different patient groups.<br /><br>In addition MBL genotypes and serum levels of these patients will be determined<br /><br>to get more insight in the differences between the groups. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>