Dexmedetomidine Versus Ketamine on Laryngeal Microsurgery
- Conditions
- Microlaryngeal Surgery
- Registration Number
- NCT07048873
- Lead Sponsor
- Cairo University
- Brief Summary
compare effect of IV dexmedetomidine and ketamine on pain score, perioperative hemodynamics and detect side effects of dexmedetomidine and ketamine.
- Detailed Description
Microlaryngeal surgery is a common surgical procedure now a days which is associated with many complications such as postoperative pain, airway edema and persistent cough
. the study is to compare the effect of IV dexmedetomidine and ketamine on pain score, perioperative hemodynamics and to detect side effects of dexmedetomidine and ketamine.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 168
- aged 18-70 years ASA I,II
-
CVdiseases as IHD and severe valvular disease.
- allergy to ketamine or dexmedetomidine.
- Patients refusal
- Suspected difficult intubation more than 2 trials
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method incidence of postoperative sore throat 30 minutes postoperative incidence of postoperative sore throat
- Secondary Outcome Measures
Name Time Method oxygen saturation 1hour postoperative oxygen saturation
Ramsey sedation score 1hour postoperative Ramsey sedation score RSS (1 to 6)
postoperative cough incidence 1hour postoperative postoperative cough incidence
incidence of complications 1hour postoperative incidence of complications
Heart Rate 1hour postoperative Heart Rate
Mean Arterial Pressure 1hour postoperative Mean Arterial Pressure
Trial Locations
- Locations (1)
Faculty of medicine Cairo university
🇪🇬Cairo, Egypt
Faculty of medicine Cairo university🇪🇬Cairo, Egypt