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临床试验/NCT06039059
NCT06039059已完成不适用

Influence of Risk Factors Such as Serum Cholesterol Level on ISR and Nonintervened Coronary Lesions

RenJi Hospital1 个研究点 分布在 1 个国家目标入组 510 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
510
试验地点
1
主要终点
LDL-C, mmol/L

研究概览

简要总结

This study enrolled patients who used to received PCI therapy with nonintervened coronary lesions. Baseline characteristics and laboratory testing were collected to find out the risk factor difference between ISR and nonintervened coronary lesions.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • (1) PCI therapy with drug-coated stents was performed in the past, and nonintervened coronary lesion remained except in the target vessel.
  • (2) CAG was performed again due to re-examination, recurrent angina symptoms, positive treadmill exercise test or coronary CTA showing moderate to severe vessel diameter stenosis.
  • (3) Long-term regular oral administration of statins and lipid monitoring were conducted after PCI.

排除标准

  • Patients with a history of CABG, renal replacement therapy, autoimmune disease, and malignancy

结局指标

主要结局

LDL-C, mmol/L

时间窗: Blood samples were collected after a 12-hour fast before CAG.

Low-density cholesterol (LDL-C) is the cholesterol in low-density lipoprotein (LDL), which reflects how much LDL is present.

次要结局

  • HbA1c, %(Blood samples were collected after a 12-hour fast before CAG.)
  • ALT, U/L(Blood samples were collected after a 12-hour fast before CAG.)
  • Scr, mmol/L(Blood samples were collected after a 12-hour fast before CAG.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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