Effects of mineralocorticoid receptor antagonists on sex hormones and body composition in patients with primary aldosteronism
Not Applicable
- Conditions
- Primary aldosteronism
- Registration Number
- JPRN-UMIN000037657
- Lead Sponsor
- Tokyo Women's Medical University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with secondary hypertension (endocrine hypertension, renovascular hypertension) without primary aldosteronism Patients with essential hypertension Subclinical Cushing syndrome patients Patients with moderate or more impaired renal function (eGFR <30 mL / min / 1.73m2) Diabetic patients with microalbuminuria or proteinuria Serum K value 5.0 mEq / L or more Pituitary hypofunction / hypogonadism patients Patients who have taken MR antagonists in recent 8 weeks Patients with embedded metal parts such as pacemakers Momentum (AES) 1800 METs min / week or more Other patients who are deemed inappropriate by the study director
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in muscle mass before and after treatment with spironolactone and esaxerenone
- Secondary Outcome Measures
Name Time Method