The effect of a mineralocorticoid receptor antagonist eplerenone on morning home BP in drug-resistant hypertensio
Not Applicable
- Conditions
- drug-resistant morning hypertension
- Registration Number
- JPRN-UMIN000014186
- Lead Sponsor
- Jichi Medical University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1.Diabetes with albuminuria or proteinuria 2.Allergy, or allergic reaction to study drugs 3. Patients with Hyperkalemia or serum potassium level>5.0mEq/ 4.Renal dysfunction (Ccr<50ml/min) 5.Sevre Hepatic damage 6.Taking potassium, or spironolactone 7.Taking Itraconazole, Ritonavir, and Nelfinavir 8. age<20yrs, or dementia 9. Not appropriate for the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Antihypertensive effects of home blood pressure between group I and II in the interventional period 1, and group III and IV in the interventional period 2 will be compared.
- Secondary Outcome Measures
Name Time Method