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Comparison of dexmedetomidine and remimazolam in conscious sedation for percutaneous thermal ablation of liver tumor: a randomized controlled study

Not Applicable
Completed
Conditions
Neoplasms
Registration Number
KCT0008873
Lead Sponsor
Samsung Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
90
Inclusion Criteria

conscious sedation for percutaneous thermal ablation of liver tumor
ASA class I - III

Exclusion Criteria

1) contraindicated for benzodiazepine-class medication administration (e.g., patients with a known allergy to the drug or a history of hypersensitivity reactions).
2) the patient refuses

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Patient satisfaction was expressed by the PSSI
Secondary Outcome Measures
NameTimeMethod
Satisfaction of interventionist (1 : Very dissatisfied ~ 5 : Very satisfied);Satisfaction of anesthesiologist (by CSSI questionnaire);Hemodynamic stability (incidence of hypotension(MBP<65mmHg), hypertension(MBP>100mmHg) or bradycardia (<45beats/min), use of drugs);Adverse effect related procedure (Failure of complete ablation - CT findings, hemorrhage(;Sedation level (MOAA/S scale);Time to Respond After Procedure Completion;Dosage of drugs (dexmedetomidine, remimazolam, remifentanil);conscious level in recovery room (RASS);pain score (NRS 0-10);Nause and vomiting (0:none 1:mild 2:moderate 3:severe);Level of memory recall during the procedure
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