Comparison of intravenous remimazolam and dexmedetomidine for sedation in patients undergoing surgery under spinal anesthesia

Not Applicable

Conditions: Diseases of the musculoskeletal system and connective tissue

Registration Number: KCT0007547

Lead Sponsor: Dong-A University Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 74

Inclusion Criteria

American Society of Anesthesiologists physical status classification I, II, or III.
- Patients aged 20 to 80 who agreed to participate in the study.
- Patients undergoing surgery under spinal anesthesia performed at Dona-A university hospital

Exclusion Criteria

- Patients with hypersensitivity to remimazolam and other benzodiazepines and to dexmedetomidine.
- Patients with puncture site infection.
- Patients with bleeding tendency.
- Patients with a history of spinal surgery.
- Patients with severe spinal deformity or spinal stenosis.
- Emergency operation.
- Patients with morbid obesity(BMI >35)
- Patients who are in the intensive care unit or who are scheduled to be transferred to the intensive care unit after surgery.
- Maternity or lactating woman.
- Patients who are unable to communicate and have cognitive impairment.
- patient's refusal

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of intraoperative and postoperative bradycardia

Secondary Outcome Measures

Name	Time	Method
Changes in vital signs during intraoperative and postoperative period;Changes in the depth of sedation during intraoperative and postoperative period;Frequency of intraoperative and postoperative hypotension;Frequency of intraoperative and postoperative desaturation;atropine usage during intraoperative and postoperative period;ephedrine usage during intraoperative and postoperative period;time required to awakening after cessation of sedation;time required to recovery after cessation of sedation;PACU(Post Anesthesia Care Unit) stay time;time required to recovery of sensory block;postsedative shivering;postsedative pruritus;postsedative nausea and vomiting;postsedative pain;postsedative headache;postsedative dizziness;postsedative respiratory depression;time of first urination after operation