Effect of sodium bicarbonate 8.4% on bronchial carcinoma

Not Applicable

Recruiting

• Conditions: Cancer; Respiratory; Bronchogenic Carcinoma

• Registration Number: PACTR201602001488346
• Lead Sponsor: Mohammad Khairy El Badrawy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-24
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1-Histologically-diagnosed primary lung cancer either central lung cancer diagnosed with bronchoscopic biopsies or peripheral lung cancer diagnosed with CT or ultrasound ¿ guided biopsies.
2-Patients who are candidates for chemotherapy either because of the cell type as small cell lung cancer or advanced stage non -small cell lung cancer or early stages of lung cancer but not candidates for surgical treatment because of poor cardiopulmonary status or refusal of surgery.

Exclusion Criteria

Patients with one or more of the following:
1.Pulmonary metastasis from extrathoracic primary tumor.
2.Patients unfit for FOB.
3.Patients who are candidates for surgical resection.
4.Patients who refuse the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cathepsin B level and expression ;histopathological changes;electron microscopic changes;clinical presentation;tumor volume on radiology

Secondary Outcome Measures

Name	Time	Method
Matrix metalloproteinases-9 level and expression;Safety of the procedure