Comparison of different modes of tranexamic acid administration in patients undergoing total knee arthroplasty.

Phase 3

Completed

• Conditions: BLOOD LOSS IN TOTAL KNEE ARTHROPLASTY.; Musculoskeletal - Osteoarthritis; Surgery - Other surgery

• Registration Number: ACTRN12614000582651
• Lead Sponsor: SAMUEL J MACDESSI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-30
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 166

Inclusion Criteria

1. All the patients undergoing total knee arthroplasty under the principal investigators.
2. Able to give consent for the study.

Exclusion Criteria

1. Inflammatory arthropathy.
2. Patients currently on warfarin (Coumadin)
3.Patients on antiplatelet therapy (excluding aspirin)
4.Bleeding diathesis
5.Haematological dysfunction/Abnormal coagulation studies
6. Patients requiring lateral release, synovectomy, or removal of existing hardware during their procedure
7. Renal or liver disease
8. Previous thromboembolic disease
9. Disturbance of colour vision
10.Stroke
11. Pre-operative anemia (Hb < 120 for females and Hb < 130 for males).

Study & Design

• Study Type: Interventional
• Study Design: Not specified