NCT04993196招募中不适用
Quantitative T1rho Magnetic Resonance Imaging in Healthy Subjects
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- T1rho value in normal grey and white matter in healthy volunteers
研究概览
简要总结
T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution.
In this study we aim to characterise the normal appearance of T1rho in the brain parenchyma in healthy participants. T1rho values will be measured in normal brain structures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Male and female volunteers greater than or equal to 18 years of age
排除标准
- •Subjects with a contraindication to magnetic resonance imaging such as the presence of metallic implants, claustrophobia and pregnancy.
- •Subjects with previous severe allergic or anaphylactoid reaction to a gadolinium contrast agent, or contraindication to contrast gadolinium administration, such severe renal disease or acutely deteriorating renal function, who would be at risk of nephrogenic systemic fibrosis
- •Subjects who are unable to tolerate the scan without moving the head as a result of symptoms such as tremor, spasticity, involuntary movements and spasms, cognitive impairment, coughing, and shortness of breath.
结局指标
主要结局
T1rho value in normal grey and white matter in healthy volunteers
时间窗: Up to 2 months
T1rho value (measured on T1rho weighted MRI) in normal grey and white matter in healthy volunteers
次要结局
未报告次要终点
研究者
Professor Tiffany So
Clinical Assistant Professor
Chinese University of Hong Kong
研究点 (1)
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