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临床试验/NCT04993196
NCT04993196招募中不适用

Quantitative T1rho Magnetic Resonance Imaging in Healthy Subjects

Chinese University of Hong Kong1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
30
试验地点
1
主要终点
T1rho value in normal grey and white matter in healthy volunteers

研究概览

简要总结

T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution.

In this study we aim to characterise the normal appearance of T1rho in the brain parenchyma in healthy participants. T1rho values will be measured in normal brain structures.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • - Male and female volunteers greater than or equal to 18 years of age

排除标准

  • Subjects with a contraindication to magnetic resonance imaging such as the presence of metallic implants, claustrophobia and pregnancy.
  • Subjects with previous severe allergic or anaphylactoid reaction to a gadolinium contrast agent, or contraindication to contrast gadolinium administration, such severe renal disease or acutely deteriorating renal function, who would be at risk of nephrogenic systemic fibrosis
  • Subjects who are unable to tolerate the scan without moving the head as a result of symptoms such as tremor, spasticity, involuntary movements and spasms, cognitive impairment, coughing, and shortness of breath.

结局指标

主要结局

T1rho value in normal grey and white matter in healthy volunteers

时间窗: Up to 2 months

T1rho value (measured on T1rho weighted MRI) in normal grey and white matter in healthy volunteers

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Professor Tiffany So

Clinical Assistant Professor

Chinese University of Hong Kong

研究点 (1)

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