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临床试验/NL-OMON44050
NL-OMON44050招募中不适用

Ventilator-Induced Diaphragm Dysfunction in ICU patients - Diaphragm weakness in the IC

Academisch Medisch Centrum0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
150

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • -Mechanically ventilated septic patients in the ICU planned for a laparotomy for suspected or proven intra-abdominal sepsis (incidence: ~50 p year), and mechanically ventilated non-septic patients in the ICU planned for a laparotomy or thoracotomy for other reasons such as trauma, abdominal haemorrhage, vascular surgery and patients scheduled for a thoracotomy for removal of a small (T1-T2) pulmonary tumor (these will serve as control subjects).
  • -Age: >18 years
  • -Gender: both male and female
  • -all ethnic backgrounds

排除标准

  • -COPD (GOLD stage II-IV) or CHF (NYHA class III-IV)
  • -Neuromuscular disease
  • -Drugs known to alter muscle structure and function
  • -Chronic metabolic disease
  • -Pulmonary hypertension
  • -Chronic use of corticosteroids (defined as >7.5 mg/day for at least 3 months)
  • ->10% weight loss within last 6 months.

研究者

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