Development of human cellular models for motor neuron diseases using disease-specific induced pluripotent stem (iPS) cells
Not Applicable
- Conditions
- Adult-onset motor neuron diseases (MND) including sporadic or familial amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) type IV
- Registration Number
- JPRN-UMIN000011542
- Lead Sponsor
- Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
- Presence of dementia - Difficulty in sampling
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Biological property of cultured neural cells differentiated from ALS/MND-specific iPS cells, such as cellular morphology, neurite elongation, synaptogenesis, and action potentials
- Secondary Outcome Measures
Name Time Method