Influence of the dietary history on the prevention of celiac disease: continuation of the PreventCD study (PreventCD2).

Recruiting

• Conditions: gluten enteropathy; gluten intolerance; 10025477

• Registration Number: NL-OMON50621
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

In order to be eligible to participate in this study, a subject must already be
participating in PreventCD-1. Inclusion criteria for PreventCD-1 were: the
child had to have at least 1 first degree relative with CD, had to be positive
for HLA-DQ2 and/or DQ8 and its parents/guardians had to give informed consent
for the study.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study: no informed consent.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Frequency of CD in the participants at the age of 18 years, according to the<br /><br>ESPGHAN guidelines.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary: to determine (1) the association of the baseline variables and (2)<br /><br>the duration of breastfeeding, daily gluten intake and infections on the<br /><br>development of CD at age 18 years; and to clarify, during and after puberty,<br /><br>the intriguing differences observed before puberty between males and females,<br /><br>especially in these with the highest risk for CD (HLA-DQ2 homozygotes)</p><br>