Effects of auditory stimulation during NREM sleep on mood
- Conditions
- Healthy subjects
- Registration Number
- JPRN-UMIN000044417
- Lead Sponsor
- niversity of Tsukuba
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 16
Not provided
Participants will be excluded from the experiment based on the following criteria. 1)BMI less than 18.5 or greater than 25 2)Worked night shifts (after 10pm) 3 months prior to the experiment 3) Travel across time zones with time Difference of 3 hours or more, 3 months prior to the experiment 4) Consumes alcohol regularly (40g (2 cans of beer) or more twice a week a more) 5)Smoker 6) Consumes more than 400 mg (Based on the maximum caffeine intake of healthy adults without adverse effects [European Food Safety Authority, Health Canada],5 cups of 150mL) of coffee every day 7) MEQ score of less than 30 (extreme evening type) or greater than 70 (extreme morning type) 8) Those who cannot perceive the auditory stimulation and feel uncomfortable when listening to samples of this experiment. 9) Pregnancy or its possibility 10) Lactation 11) Those who have a disease that may change suddenly or its history 12) Those who have been treated for psychiatric disorders or sleep disorders, and those who have symptoms that are currently being treated 13)Candidates of Participants who follow all inclusion criteria, but exclusion criteria 1) -12) will be reported to psychiatrist. Psychiatrist interviews as needed to determine the unsuitable person as a subject. 14) Subjects judged by the principal investigator to be inappropriate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Subjective anxiety using the questionnaire(State-Trait) Anxiety Inventory - subscale scores of state anxiety)
- Secondary Outcome Measures
Name Time Method 1)The change of power in the slow wave activity frequency with and without auditory stimuli 2)Amplitude of slow wave 3)Sleep variables obtained by polysomnography 4)Heart rate variability 5)Electroencephalogram (EEG) 6)Electrooculogram (EOG) 7)Electromyogram (EMG) 8)Respiration 9)The changes of skin conductance change 10)Psychomotor vigilance test performance 11)Subjective sleepiness by a questionnaire (Karolinska Sleepiness Scale) 12)Subjective sleep evaluation after waking up (Oguri-Shirakawa-Azumi Sleep inventory) 13)Subjective mood and affect (Profile of Mood State 2, Positive and Negative Affect Schedule) 14)Characteristic waves of sleep EEG