ACTRN12611000874910已完成不适用
A comparison of the effect of bi-level ventilatory support versus continuous positive airway pressure on the rates of treatment failure in patients with stable obesity hypoventilation syndrome
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Primary diagnosis of Obesity Hypoventilation Syndrome
- •Body mass index >30kg.m-2
- •Daytime respiratory failure with a PaCO2>45mmHg
- •At randomization, pH is in the normal range for chronic hypercapnia
- •FEV1/FVC ratio >70%
排除标准
- •Hypoventilation attributable to other causes eg neuromuscular disease, chest wall abnormalities, multiple medications with sedative/respiratory depressant side-effects
- •Physician diagnosed chronic obstructive pulmonary disease
- •Has used non-invasive ventilation (Bilevel PAP or CPAP) for more than one month in the previous 3 months.
- •Not proficient in English
- •Inability to provide informed consent
研究者
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