ACTRN12612000815864
Not yet recruiting
未知
Effects of two different ventilatory modes i.e., neurally adjusted ventilatory assist and pressure support ventilation on duration of mechanical ventilation and intensive care unit lenght of stay in patients with acute respiratory failure. A multicenter randomized clinical trial.
Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.0 sites180 target enrollmentAugust 3, 2012
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Duration of mechanical ventilation during acute respiratory failure
- Sponsor
- Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.
- Enrollment
- 180
- Status
- Not yet recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Intubated patients
- •Previous mechanical ventilation \>\= 24 hours
- •Ability to effectively trigger the ventilator
- •Expected ventilatory assistance \>\= 48 hours
- •No scheduled surgery
- •No inclusion in other research protocol
- •No neuromuscular or neurologic disease
- •Absence of contraindications to feeding tube positioning (including esophageal surgery in the previous 12 months and/or history of esophageal varices)
- •PaO2/FiO2 \>150 with PEEP \>\= 5 cmH2O
Exclusion Criteria
- •Lack of informed consent or refusal
- •Organ failure \>\= 3
- •Poor short term prognosis or decision to limit life support
Outcomes
Primary Outcomes
Not specified
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