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Clinical Trials/ACTRN12612000815864
ACTRN12612000815864
Not yet recruiting
未知

Effects of two different ventilatory modes i.e., neurally adjusted ventilatory assist and pressure support ventilation on duration of mechanical ventilation and intensive care unit lenght of stay in patients with acute respiratory failure. A multicenter randomized clinical trial.

Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.0 sites180 target enrollmentAugust 3, 2012

Overview

Phase
未知
Intervention
Not specified
Conditions
Duration of mechanical ventilation during acute respiratory failure
Sponsor
Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.
Enrollment
180
Status
Not yet recruiting
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 3, 2012
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.

Eligibility Criteria

Inclusion Criteria

  • Intubated patients
  • Previous mechanical ventilation \>\= 24 hours
  • Ability to effectively trigger the ventilator
  • Expected ventilatory assistance \>\= 48 hours
  • No scheduled surgery
  • No inclusion in other research protocol
  • No neuromuscular or neurologic disease
  • Absence of contraindications to feeding tube positioning (including esophageal surgery in the previous 12 months and/or history of esophageal varices)
  • PaO2/FiO2 \>150 with PEEP \>\= 5 cmH2O

Exclusion Criteria

  • Lack of informed consent or refusal
  • Organ failure \>\= 3
  • Poor short term prognosis or decision to limit life support

Outcomes

Primary Outcomes

Not specified

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