Repeated corticosteroid injections around the Greater Occipital Nerve (GON) as prophylactic treatment in chronic cluster headache

Phase 3

Recruiting

• Conditions: Clusterheadache; Trigeminal Autonomic Cephalalgias; 10019231

• Registration Number: NL-OMON56462
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

- Age >=18
- Chronic cluster headache (International Classification of Headache Disorders
- third edition; ICHD-3)
- Ictal pain must be always at the same side
- >=4 weekly attacks of cluster headache in the prospective one-month baseline
observation period
- On a stable regimen of cluster headache prophylactics for >4 weeks prior to
onset of study treatment and agreeing not to increase the dose and not starting
a new cluster prophylactic during the study period

Exclusion Criteria

- Contra-indication against, or current use of, corticosteroids
- Occipital nerve stimulation (ONS)
- Use of anticoagulation medication or a known bleeding disorder
- Inability to use an electronic diary to monitor individual attacks and other
items
- Other headaches if the patient cannot reliably distinguish them from attacks
of cluster headache
- Current use of prophylactic medication for other headaches
- Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified