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Comparative outcomes of thromboprophylaxis between low molecular weight heparin (LMWH) and rivaroxaban in surgical gastrointestinal cancer patients

Not Applicable
Conditions
rivaroxaban &#44
thromboprophylaxis
thromboprophylaxis &#44
surgical &#44
cancer
Registration Number
TCTR20190712003
Lead Sponsor
Ramathibodi hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
760
Inclusion Criteria

age > 18 years
gastrointestinal cancer
surgery

Exclusion Criteria

previous venous thromboembolism
Preoperative DVT
Coadministration of anticoagulant medication
rivaroxaban drug allergy
active clinical bleeding
poor renal function (GFR < 30)
impair liver function (Child-Pugh B and C)
History of heparin induced thrombocytopenia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Venous thromboembolism 1 month Ultrasound
Secondary Outcome Measures
NameTimeMethod
bleeding complication 1 month clinical diagnosis,cost&#45;effectiveness 1 month cost of treatment,satisfaction scores 1 month record form
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