Study in platelet matching on blood cancer patients.
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: D47Z- Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
- Registration Number
- CTRI/2023/06/053410
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
•No episode of bleeding at the time of inclusion of patients
•Platelet refractory hemato-oncological patients( diagnosis:-aplastic anemia, acute myeloid leukemia, lymphoma, acute lymphoid leukemia, multiple myeloma)with thrombocytopenia having CCI count less than 5,000 at 24 hours post transfusion after two consecutive Single donor Apheresis platelet (SDAP) transfusions
Exclusion Criteria
non refractory cases
patients having Pyrexia
Patients with infection(viral, bacterial and fungal)
Patient on drugs causing TCP
Bleeding episode
DIC
Splenomegaly
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To note and compare CCI,PPR after transfusion of SDAP units.Timepoint: 24hors post transfusion.
- Secondary Outcome Measures
Name Time Method To check bleeding and change in transfusion interval.Timepoint: 24hours post transfusion to 1week.