A clinical study to compare the effectiveness of reducing post operative sore throat in tonsillectomy following dexmedetomidine intraoral spray versus ketamine intraoral spray
Phase 4
- Conditions
- Health Condition 1: J350- Chronic tonsillitis and adenoiditis
- Registration Number
- CTRI/2024/03/063919
- Lead Sponsor
- Dr Ranadhee Paul
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Only ASA I and II without any anticipated difficult airway (MPS -I & II) will be included .
2.Patients between age 12-30 years
3.Patients of both sexes
4.Patients scheduled for elective tonsillectomy under general anaesthesia
Exclusion Criteria
1.Refusal to valid informed consent.
2.History of allergy to the study drugs.
3. Patients with Cardiovascular, respiratory, renal , hepatic or neuromuscular diseases.
4. Patients with a history of preoperative sore throat, asthma, respiratory tract infection,consumption of analgesic in preoperative period, operating time more than 90 minutes, and requirement of more than one attempt for passage of endotracheal tube.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine whether Dexmedetomidine or Ketamine intraoral spray is more effective in attenuating the post-operative sore throat in tonsillectomy.Timepoint: Comparing the time required for attenuation of sore throat in the two groups of participants at 0 hour, 2 hours, 6 hours 12 hours 18 hours and 24 hours post operatively.
- Secondary Outcome Measures
Name Time Method To evaluate any adverse effects of the drugs used i.e. Dexmedetomidine & Ketamine intraoral spray.Timepoint: To evaluate adverse effects of the drugs at 0 hour, 2 hours, 6 hours, 12 hours, 18 hours, 24 hours post operatively