The impact of timed protein supplementation to maximize the skeletal muscle adaptive response with endurance exercise training in young healthy me

Completed

Conditions: Effect van duurtraining met eiwitsuppletie op spier en bloed
Not applicable

Registration Number: NL-OMON45535

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 44

Inclusion Criteria

* Male
* Age between 18 and 30 years of age
* BMI between 18.5 * 25 kg/m2
* Recreationally active, performing sports on a non-competitive basis
* Wmax * 5 *kg
* Willing to give muscle biopsies
* Willing to give blood samples
* Having a general-practitioner
* Consumption of alcohol beverages is less than 21 per week
* Able to perform three exercise sessions weekly for 12 weeks

Exclusion Criteria

* Medical condition that can interfere with the study outcome (i.e. cardiovascular disease, pulmonary disease, liver or renal disease, diabetes mellitus type 1 or 2)
* Having a lactose and/or gluten intolerance
* Use of systemic medication (with the exception of antihistaminic medication and the use of occasional painkillers)
* (Chronic) injuries of the locomotor system (e.g. musculoskeletal/orthopedic disorders) that can interfere with the intervention
* Participants who are enrolled in an interventional biomedical research project or have received an investigational new drug or product with the last 30 days prior to screening.
* Smokers and use of illicit drugs
* Blood donor during the study and in the three months before start of the study
* Employed, or intern, or working on a thesis at the department of Human Nutrition at Wageningen University & Research
* Participating in another scientific study (except EetMeetWeet)

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>VO2max</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>10-km time trial<br /><br>Muscle Fiber Adaptations<br /><br>capillary density<br /><br>gene expression<br /><br>phosphorylation proteins<br /><br>mitochondrial mass<br /><br>Cytochrome synthesis activity<br /><br>blood parameters<br /><br>body Composition<br /><br>waist circumference<br /><br>body weight<br /><br>BMI</p><br>