The Effectiveness of Oral Acyclovir in the Treatment of Molluscum Contagiosum in Children
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- The percentage of patient with complete clearance of all molluscum lesions.
研究概览
简要总结
The investigators will study the effectiveness of acyclovir in the treatment of molluscum contagiosum in assiut university hospital - dermatological out patient clinic the treatment group will receive acyclovir 200 mg 5 times per day the controlled group will receive local KOH solution
详细描述
Study population:
Site of the study: The outpatient dermatological clinic in Assiut university hospital.
Participants: children (2 -16) years' old attending dermatological clinic in Assiut university hospital and their parents.
Methodology in details:
- We will use the social media as " Facebook" to invite patient to visit the clinic and follow up them due to the protective measures of covid 19.
- Diagnosis of the patient with molluscum contagiosum according to the clinical picture
- Collecting data including personal and clinical data through interviewing the patient and his or her parents
- Pictures of the lesions will be taken before and after treatment after patient consent.
- We will Randomly assigning the patient to either treatment group or controlled group according to simple random table
- Prescribing the treatment according to the patient group
- Follow up of the patient after 1 weak and each week according to the response to treatment or presence of complication
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 2 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children (2 -16) years old with Molluscum contagiosum.
排除标准
- •Molluscum contagiosum with Inflamed spot Known immune compromised children Molluscum lesion in the eye lid. Children with renal impairment.
研究组 & 干预措施
treatment group
200 mg of oral acyclovir 5 timed per day for 5 days per week for maximum 1 month
干预措施: Acyclovir (Drug)
controlled group
KOH 10 % solution local application with apiece of cotton 2 time per day maximum for 1 month
干预措施: KOH 10 % (Drug)
结局指标
主要结局
The percentage of patient with complete clearance of all molluscum lesions.
时间窗: 3 month for each participant
we will measure the percentage of patient recovered from all lesion
次要结局
未报告次要终点
研究者
Dalia Mahran
professor of public health and community medicine
Assiut University