Obesity Treatment Enhanced With Working Memory Training

Not Applicable

Completed

• Conditions: ADHD; Weight Loss
• Interventions: Behavioral: Adaptive Working Memory Training; Behavioral: Non-adaptive cognitive training

• Registration Number: NCT02529397
• Lead Sponsor: University of Vermont

Brief Summary

This study will examine the effects of providing subjects who have attention deficits, with or without a formal diagnosis of attention deficit hyperactivity disorder (ADHD), with Working Memory computerized training and explore whether this training is a feasible way to help them better engage in a weight loss treatment program, thereby enhancing weight loss results. Half of the participants will receive five weeks of online adaptive WM training concurrently while attending an in-person 24-week behavioral weight management program and half will receive five weeks of a non-adaptive form of cognitive training concurrently while attending a 24-week behavioral weight management program in person.

Detailed Description

Populations with ADHD or attention issues tend to have more weight loss attempts, struggle more with losing weight, and drop out of treatment more frequently than those without attention difficulties. Adaptive working memory training has been used to strengthen working memory and to mediate the symptoms associated with ADHD. The adaptive training becomes progressively more challenging as participants master each level of the training, while non-adaptive training remains at the same level throughout. Both groups will attend 24 weekly, in-person weight management classes on the University of Vermont Campus. Both groups will do cognitive training on their own home computers five days a week for 30-40 minutes for five weeks concurrently while engaged in the weight loss program.

Study Timeline

• Study First Submitted: 2015-08-18
• Study First Submitted QC: 2015-08-18
• Study First Posted: 2015-08-20
• Study Start: 2015-10
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-24
• Last Update Posted: 2016-10-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Must score 4 or higher on the ASRS v. 1.1
• Must live within 45 minutes driving distance from UVM campus
• Must be able to exercise
• Must have a computer with internet access and ability to utilize flash
• Must be 18 or older

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Exclusion Criteria

• Health issues that preclude exercise
• use of medications that interfere with the ability to lose weight
• vacation longer than two weeks
• current participation in another weight loss program
• reside more than 45 minutes from UVM campus in Burlington
• no internet access, no home computer, or computer cannot use flash

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Adaptive Working Memory Training	Adaptive Working Memory Training	The experimental group will receive working memory training through a commercial computerized program: five weeks of adaptive working memory training concurrently with a behavioral weight loss program. Adaptive working memory training becomes progressively more challenging depending on an individual's performance on a given task. They will attend weekly classes of a behavioral weight loss program.
Non-adaptive Working Memory Training	Non-adaptive cognitive training	The control group will receive five weeks of non-adaptive (placebo) cognitive training concurrent with the identical behavioral weight loss program as in the experimental group. Non-adaptive cognitive training remains at a constant level.

Primary Outcome Measures

Name	Time	Method
Weight	24 weeks	Participants weight at baseline will be compared to their weight at 24 weeks at the completion of the study.

Trial Locations

Locations (1)

Behavioral Weight Management Program/Univ of Vermont; 🇺🇸 Burlington, Vermont, United States