Future Mental Projections in Schizophrenia

Terminated

• Conditions: Schizophrenia
• Interventions: Other: questionnary

• Registration Number: NCT03040505
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The aim of the study is to investigate temporal organization of future thinking in patients with schizophrenia. Patients and control participants will be asked to envision and briefly describe ten personal future events using a cue-words list. Then they will be asked to describe everything that came to their minds (i.e. to think aloud) while they attempted to determine when an event will likely occur. The investigators will compare the proportion of several predefined strategies mentioned by the two groups of participants to locate future events in time. The investigators predict that patients will envision less personal future events and will rely to a lesser extent on strategies to locate events in time, than control participants.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-01-27
• Study First Submitted QC: 2017-01-31
• Study First Posted: 2017-02-02
• Study Start: 2017-04-05
• Primary Completion: 2019-10-20
• Study Completion: 2019-10-20
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-21
• Last Update Posted: 2023-08-23

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• for patients only
• male or female
• age limits : 18-55 years old
• under the protection of health insurance
• who have signed up the consent form
• schizophrenia or schizo-affective disorder according to the DSM-5 criteria (APA, 2013).
• clinically stable for at least 2 months
• patients under guardianship or curatorship need agreement of their legal representative
• informed of the results of prior medical examination for controls only
• male or female
• age limits : 18-55 years old
• under the protection of health insurance
• who have sign up the consent form
• recruited from the general population and matched on gender, age years of schooling
• no psychiatric history (DSM-5)

Exclusion Criteria

• for both patients and controls
• current severe or unstable somatic illness
• neurological history (brain injury > 15 minutes loss of consciousness , epilepsia, brain surgery...)
• current substance use disorder (DSM-5)
• current major depressive disorder (CDSS,BDI, HDRS)
• mental retardation (IQ < 70, WAIS-4, f-NART)
• history of general anesthesia 3 months prior to the experiment
• pregnancy declared by the subject
• breast feeding
• current legal control
• in emergency situation
• included during exclusion period in another experiment
• for controls only
• taking of antipsychotic drugs for the 3 weeks prior to inclusion
• under guardianship or curatorship

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control participants	questionnary	- Control participants without psychiatric nor neurological history
Patients with schizophrenia	questionnary	Patients with schizophrenia or schizoaffective disorder according to DSM-V criteria

Primary Outcome Measures

Name	Time	Method
Number of time location strategies	1 months

Trial Locations

Locations (1)

Service de psychiatrie 1; 🇫🇷 Strasbourg, France