Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance
Not Applicable
Completed
- Conditions
- Altitude Hypoxia
- Interventions
- Other: Simulated altitudeOther: Placebo simulated altitude
- Registration Number
- NCT03743610
- Lead Sponsor
- Mayo Clinic
- Brief Summary
The investigators expect to find that different intensity and altitude exposure levels will show what kind of intermittent exposure protocol is more beneficial to athletes and healthy individuals that experience acute exposure to altitude during exercise. This may furthermore be related to acute altitude exposure for recreational exercise use as well.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 71
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Effect of heart rate training in simulated altitude Simulated altitude Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining \>65% max heart rate during room air based maximal peak work. Effect of optimized training in simulated altitude Simulated altitude Participants will perform the more beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether it improves elite athlete's training status at altitude. Effect of saturation of oxygen training in simulated altitude Simulated altitude Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining 40-60% of max work rate during room air work rate and based upon saturation of oxygen of between 70-80%. Effect of placebo training in non-simulated altitude Placebo simulated altitude Participants will perform placebo beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether the optimized protocol truely improves elite athlete's training status at altitude.
- Primary Outcome Measures
Name Time Method Change in hemoglobin Baseline, 2-week, 4-week, 6-week, and 8-week Change in hematocrit Baseline, 2-week, 4-week, 6-week, and 8-week Change in erythropoietin Baseline, 2-week, 4-week, 6-week, and 8-week
- Secondary Outcome Measures
Name Time Method Change in peak VO2 Baseline and 6- and 8-week Change from maximal exercise test performed at sea level
Change in cycling performance at altitude Baseline and 6- and 8-week change in aerobic/anaerobic cycling performance at altitude
Trial Locations
- Locations (1)
Mayo Clinic in Arizona
🇺🇸Scottsdale, Arizona, United States