Does a new mechanical ventilation strategy in the immediate postoperative period of cardiac surgery reduce pulmonary complications and is it capable of optimizing the functional capacity of patients at hospital discharge?

Not Applicable

• Conditions: Cardiac surgical procedures; Other post-procedure respiratory disorders; E04.292

• Registration Number: RBR-2nmwxwt
• Lead Sponsor: Hospital Universitário Pedro Ernesto (HUPE)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-05
• Study Completion: 2023-11-30
• Last Update Posted: 2 April 2024

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients aged 18 years or over, undergoing elective cardiac surgery for valve replacement (VT) or myocardial revascularization (MVR) or VT with CABG; surgery in the ascending Aortic Artery associated with cardiac surgery; correction of atrial septal defect (ASD); correction of interventricular communication (IVC) with programmed use of cardioplumonary bypass (CPB), clamping of the aorta artery, use of cardioplegia and conventional median sternotomy or median ministernotomy, volume adjusted to an inferior vena cava (IVC) measurement above 18 mm and mean arterial pressure ( MAP) greater than 80 mmHg.

Exclusion Criteria

Patients who refuse to participate in the study will be excluded; patients with previous cardiac surgery; pulmonary fibrosis; pulmonary emphysema; pneumonia diagnosed in the last 30 days; patients with pulmonary artery hypertension, with pulmonary artery systolic pressure greater than 45 mmHg; need for orotracheal intubation before arrival in the operating room; obese with body mass index (BMI) greater than 40 kg/m2; need for noradrenaline greater than 2 µg/kg/min; need for re-operation; pneumothorax and/or bubbling drains; patients with neuromuscular disease; myocardial revascularization surgery (CRVM) using a right internal mammary artery (MID) and radial artery graft.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to compare the incidence of postoperative pulmonary complications (PPCs) using the modified Kroenke pulmonary complications score.

Secondary Outcome Measures

Name	Time	Method
It is expected to analyze, in a comparative way, the pulmonary mechanics.;It is also expected to evaluate the implementation of the new mechanical ventilation protocol in the postoperative period of Cardiac Surgery at Hospital Pedro Ernesto (HUPE).;It is expected to analyze, in a comparative way, the performance in the 6-minute walk test (6MWT).;It is expected to analyze, in a comparative way, the length of stay in the intensive care unit (ICU).;It is expected to analyze, in a comparative way, the relationship between the fraction of inspired oxygen (FiO2) and the arterial partial pressure of oxygen (PaO2).