Cord Milking and Activity Of The Immune System In Preterm Infants

Not Applicable

• Conditions: Preterm Delivery
• Interventions: Other: CORD MILKING

• Registration Number: NCT02043249
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

In the embry life there is a passage of IgG type, from the mother to tha embryoyo and only in the age of 3-5 month after birth the infant start to develop them by himself.

In preterm infants the starting point of the level of the IgG's is lower from the level of term infants.

Delayed cord clamping /milking it was prooved in many researches as benificial in terms of : levels of hemoglobin; hematocrit and feritin in the neonats. Also benefits were proved by means of less need for blood tranfusion, less intra ventricular hemorrhage; necrotzing entero colitis and iron deficiency anemia. The hypothesis is that delayed clamping /milking it will increse the level of IgG's in preterm infants. The end point hypothesis is that delayed cord clamping /milking cause to less fever disease or hospitalization it the neonats.

Detailed Description

In this study we come to a prove that if we miking the cord in preterm infats we will increse the level of IgG .

Study Timeline

• Status Verified: 2013-11
• Study First Submitted: 2013-11-13
• Study Start: 2014-01
• Study First Submitted QC: 2014-01-19
• Last Update Submitted: 2014-01-19
• Study First Posted: 2014-01-23
• Last Update Posted: 2014-01-23
• Primary Completion: 2016-01
• Study Completion: 2016-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• PRETERM INFANS BETWEEN 24+0/7 TO 36

  • 6/7 WEEKS.
  • NEWBORN FOR MOTHER WHO AGREE TO PARTICIPATE IN THE RESEARCH WHO DELIVER IN NORMAL DELIVERY / PLANED OR URGENT CESARIAN DELIVERY

Exclusion Criteria

• INTRA UTERINE GROWTH RESTRICTION, INFANT UNDER 10% TO AGE OF PREGNANCY.
• MOTHER WHO IS NOT WILLING TO PARTICIPATE IN RESEARCH.
• NEONATES TO MOTHER WHOM SUSPECTED TO BE IMMUNO- COMPROMISED OR HAVING INFECTION AROUND DELIVERY.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
CORD MILKING	CORD MILKING	WITHOUT MILKING

Primary Outcome Measures

Name	Time	Method
levels of IgG in preterm infats	24 hours after delivery and after 24 hours..	Blood test for IgG's level from the baby in : at delivery . 24 hours after delivery. before discharg from hospital

Secondary Outcome Measures

Name	Time	Method
Mother's telephone questioning about the infant disease: fiver / hospitalization/tretment wit antibiotic.	3 and 6 month after delivery	Phone call interview of the mother in 3 and 6 month from delivery about : emergengy room admission; hospitalization, fever disease and antibiotic treatment in this time period.

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel