Effect of Chlorhexidine Skin Cleansing on Skin Flora
Phase 4
Completed
- Conditions
- Skin Diseases, Infectious
- Registration Number
- NCT00198679
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Brief Summary
Given the potential of skin cleansing with chlorhexidine as a safe, feasible, and cost-effective intervention for reducing neonatal death in developing country settings, this study follows a trial already underway in Nepal to test the impact of a single cleansing of the skin with baby wipes cotaining chlorahexidine.
- Detailed Description
This study is designed to test the impact of a single cleansing of the skin with 0.25% or 4.0% Chlorhexidine wipes on qualitative and quantitative skin flora and skin condition in newborn infants. The study takes place in the Special Care Nursery at Dhaka Shishu Hospital in Dhaka, Bangladesh.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
- Infant admitted to Special Care Nursery at Dhaka Shishu Hospital less than 48 hours chronological age
- parental consent must be obtained
Exclusion Criteria
- infants being admitted for major surgical procedure which is attended by high rate of infectious complications
- sepsis
- clinically-evident skin infection
- generalized skin disease
- structural defect of the skin involving greater than 5% of the body surface
- with a major congenital anomaly
- with a known immunodeficiency
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Wiping of newborn skin will be done immediatly upon enrollment in study, with follow up during hosptial stay and up to two weeks to determine skin condition and presence of any kind of skin infection.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Dhaka Shishu Hospital
🇧🇩Dhaka, Bangladesh