Dexamethasone and Lower Extremity Block Duration

Phase 4

Terminated

• Conditions: Analgesia Duration
• Interventions: Drug: Dexamethasone; Drug: Bupivacaine

• Registration Number: NCT01756586
• Lead Sponsor: University of Chicago

Brief Summary

Dexamethasone has shown to prolong upper extremity blocks. No one ha studied its effect on lower extremity blocks. The study would evaluate that point.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-12-20
• Study First Submitted QC: 2012-12-20
• Study First Posted: 2012-12-27
• Study Start: 2013-02
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Results First Submitted: 2016-06-16
• Status Verified: 2017-05
• Results First Submitted QC: 2017-05-24
• Last Update Submitted: 2017-05-24
• Results First Posted: 2017-06-27
• Last Update Posted: 2017-06-27

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

1. Age 18-75
2. foot surgery
3. no contraindication to regional anesthesia

Exclusion Criteria

1. opioid dependent
2. chronic pain condition
3. peripheral neuropathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental	Dexamethasone	Bupivacaine with Dexamethasone
Control	Bupivacaine	Plain bupivacaine
Experimental	Bupivacaine	Bupivacaine with Dexamethasone

Primary Outcome Measures

Name	Time	Method
Increase in the Duration of Block	3 days

Trial Locations

Locations (1)

University of Chicago Medical Center; 🇺🇸 Chicago, Illinois, United States